FlyBrian
by the Pena Lab at FAU
HomeSimulator
Ventral nerve cord of Drosophila melanogaster

Neural Circuit Simulation

Exploring the Drosophila Ventral Nerve Cord

Research laboratory

Meet the lab

Sai Kate
Belle Krubitski
Lindsey Knowles
Esteban Cuadra
Ty Roachford
Rodrigo Pena
Cesar Ceballos
Juan Lopez

This site is a work in progress!

Please check back soon for updates

About FlyBrian

FlyBrian is an advanced neural circuit simulation platform designed to model and analyze the complex neural networks of the Drosophila melanogaster ventral nerve cord (VNC).

Built on cutting-edge computational neuroscience frameworks, our platform integrates high-resolution connectome data from Janelia Research Campus with sophisticated biophysical neuron models to enable detailed circuit-level simulations.

Researchers can explore neural dynamics, test hypotheses about circuit function, and investigate how specific neurons contribute to behavior through targeted stimulation and silencing experiments.

Key Features

  • High-fidelity neural circuit simulation using Brian2
  • Integration of Janelia FlyWire connectome data
  • Interactive neuron search and targeting
  • Real-time visualization of neural dynamics
  • Scalable from single neurons to full network

Research Applications

Circuit Analysis

Understand connectivity patterns and information flow

Behavioral Studies
(coming soon)

Link neural activity to motor outputs and behaviors

Optogenetics

Model targeted stimulation and silencing experiments

Development (coming soon)

Study circuit formation and plasticity